python - Creating a Smooth Line based on Points - Stack Overflow

I have the following dataset: x = [1, 6, 11, 21, 101] y = [5, 4, 3, 2, 1] and my goal is to create a smooth curve that looks like this: Is there a way to do it in Python? I have attempted using

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python - Is there a way to smooth a line between points such that the gradient at each point is 0? - Stack Overflow