Alveolar macrophages help CD8+ T cells go (anti-)viral

The human immune system is a highly complex network of cells, signals, and responses that is tightly regulated to ensure that the body can fight off infection without damaging its own tissues. Now, researchers from Japan report a new way in which the immune system protects lung tissue from viral infections.

Research outcomes

Inflammasome activation in infected macrophages drives COVID-19 pathology

Pathogen involvement in bone marrow failure (BMF). Primary viral or

Influenza-trained mucosal-resident alveolar macrophages confer long-term antitumor immunity in the lungs

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Frontiers Crosstalk Between Tumor-Associated Microglia/Macrophages and CD8-Positive T Cells Plays a Key Role in Glioblastoma

Study finds gut microbiota influence severity of respiratory viral infection

Research outcomes

CD8+ T cell activation in cancer comprises an initial activation phase in lymph nodes followed by effector differentiation within the tumor - ScienceDirect